Genetics: Analysis and Principles

Book Description

Genetics: Analysis and Principles emphasizes the scientific method to give students the insight needed to develop scientific reasoning skills. Thirty-six text-integrated experiments in transmission and molecular genetics follow the five-step scientific method as they show students the "how" (experimental procedures) and "why" (the underlying scientific principles) behind important experiments that created the current body of genetics knowledge. Chapter by chapter, students see what it is that geneticists actually do how they conduct experiments, collect data, and use problem-solving skills to interpret that data. The text challenges students to think scientifically and rely on their own careful analysis of the data scientists have collected. As a result, students experience genetics as the exciting, dynamic science that it is.

Customer Reviews:

I keep returning to this textbook.......2007-07-28

This is the only genetics book I have. However, I have completed a graduate level biochemistry course. In biochemistry, we discussed many of the subjects presented in Brooker's textbook. Despite having an excellent biochemistry text, Brooker's presentation was often superior, providing a clearer explanation.

I have heard the graphics of the text often derided; I believe this is because some of the graphics were not printed well. Often the graphics are somewhat "fuzzy." However, comparing how well the graphics in this text present concepts against how well the graphics in other texts present the same concepts has been illuminating. Another student actually brought Brooker's text to our biochem lab several times to show other students the graphics to help explain some concepts. The graphics may be fuzzy, but they get the point across.

I'm keeping this in my library. I have returned to it several times.

There is a solutions manual to go with the text. I recommend getting the solutions manual. Working the problems at the end of each chapter will provide a good understanding of the material.

nice diagrams, bad information.......2005-09-25

I recently used this book in an undergraduate genetics course that was taught by a M.D./Genetics Counselor who, after the first month or so of using the book and the accompaning powerpoint presentation got so frustrated that told us not to bother reading the book anymore. An example would be the improper use of the Chi Square test that the book uses and instructs.

If you are an instructor save yourself the trouble of dealing with a book with so many errors in it.

Excellent text for self-directed learning.......2004-05-20

I used this textbook in a distance learning course and have found it to be invaluable to my learnng experience.

For anyone who has taken Genetics, you'll account for the fact that it is not an easy course. Taking it without a professor present is even more challenging. Luckily this text is well written and easy to follow. The author uses a mix of theory and experiment examples to drive important concepts home. The language is not dry like in many Biology texts. Instead, it is easy to read, almost to the point of being enjoyable.

There are a few things I really liked:
1. The illustrations in this book are paramount to learning difficult concepts. When explaining experimental procedures, the text is accompanied by step-by-step instuctions and illustrations as to how the experiment was carried out. This proved helpful in visualizing the procedure.
2. Each chapter is well organized and easy to understand. The author speaks in easy to understand terms (that is if you have had previous Biology courses.) His writing style is dynamic and never boring.
3. Difficult concepts are often explained more than once. Sometimes the book gets a little ahead of itself, but page numbers and chapters are always given so you can read about things you don't understand.
4. The end of each chapter provides the reader with provocative critical thinking questions that solidify important points from the chapter. Best of all, even numbered answers are given in the back so you can check yourself without hunting through the book.

Overall I'd give this book an A and it will remain in my collection of Biology texts.

The Best Undergraduate Textbook I've Seen for Genetics.......2001-04-27

I've just completed my first semester teaching Genetics at a small liberal arts college in Indiana. Because I was jumping into the position I was stuck using the text previously designed for the class. Almost a third of the book was classical genetics, which I enjoy, but was certainly overplayed. Molecular Biology areas were a jumble of terms to learn and lists to inscribe into their brains. The problems in the book did not reflect the material in the text, leaving the class pretty much upset with the book. By midterm it was time to find another sources for the class.

I found myself reaching for other texts, and "Genetics, Analysis and Principles" turned out to be the jewel. It is well balanced, very clearly written, and does not spend its time making students read long memory lists of genes or proteins that the class is going to forget less than two weeks after the term. I think this is largely reflected by the way he wrote the book; with input from students.

Reading the intro I was afraid that this text was going to be way over into the experimental design/ data side which I've seen in other texts mean "no content". Not so this text; experimental design has been written into the book to describe genetics and content, not replace it. I think what is truely unique about this book is the use of scientific process as a way to teach concepts. I wish I had more books like this one for other courses. I hope Dr. Brooker's format for Biology (and yes other science courses) is adopted for other courses.

Book Description

Two-dimensional electrophoresis is the central methodology in proteome research, and the state of the art is described in detail in this text, together with extensive coverage of the detection methods available. Sufficient detail is given to allow the readers to apply these technologies to their own particular requirements.

Customer Reviews:

Necessary Text for the Neophyte.......2000-07-03

After reading the book, I better understood the fundamentals of proteomics. The book over all is well written and provides information into the new technology of proteomics that have been poorly described in other texts. Professor Rabilloud, Thanks.

Proteome Research: Mass Spectrometry (Principles and Practice)

Average customer rating:

A protein mass spectrometry book in disguise

Proteome Research: Mass Spectrometry (Principles and Practice)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

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Similar Items:

Protein Sequencing and Identification Using Tandem Mass Spectrometry

ASIN: 3540672567

Book Description

Recent advances in large-scale DNA sequencing technology have made it possible to sequence the entire genome of an organism. Attention is now turning to the analysis of the product of the genome, the proteome, which is the set of proteins being expressed by a cell. Two-dimensional gel electrophoresis can be used to create cellular protein maps which give a quantitative and qualitative picture of the proteome. Mass spectrometry is the method of choice for the rapid large-scale idenfification of these proteomes and their modifications. An understanding of these methods is critical for scientists in the "Post-Genome" era.

Customer Reviews:

A protein mass spectrometry book in disguise.......2001-07-03

Although the title of this book adopts the term "proteome" (no doubt to aid sales) it describes essentially mass spectrometry of peptides and proteins. After an introductory chapter by the editor, the next chapters are devoted to specific mass spectrometers, namely electrospray ionisation on triple quadrupoles and matrix-assisted laser desorption ionisation on time-of-flight instruments. Three chapters describe MS approaches to identify proteins including mass fingerprinting and sequencing with the aid of automated tandem MS/MS spectra interpretation. The analysis of post-translational modifications, in the form of phosphorylation and glycosylation, is described followed by a comprehensive chapter of protein databases. The book ends with chapter discussing instrument configurations and somewhat of a focus on FT-ICR's. What the book lacks is an inclusion of applications in proteome analysis by mass spectrometry. This is probably because there is very little published data on the subject, while the "proposed" research has received considerable mileage. Another curious feature of this text is the selection of authors. Of particular note is the editor who tackles the chapters on protein mass fingerprinting and interpreting tandem mass spectrometry despite a lack of publications in both areas. Little wonder then section 8.2.4 spends some time discussing charge-localisation and its influence on peptide fragmentation for low energy MS/MS spectra and not high-energy collision spectra where this phenomenon is far more evident. In short, a possibly useful book if you have the dollars to spare. If not, head to your book shelf or library for one on protein mass spectrometry. There's not much new here.

Genetic Analysis: Principles, Scope and Objectives

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Genetic Analysis: Principles, Scope and Objectives

Manufacturer: Blackwell Publishing Limited
ProductGroup: Book
Binding: Paperback

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Book Description

Authored by a very eminent geneticist, this text gives students a thorough appreciation of the development and potential of analytical genetic techniques. Beginning with a consideration of both the classical mendelian and the molecular biological aspects of genetic analysis, the book goes on to discuss progress in three key areas of genetics. Firstly the elucidation of the detailed structure and overall organization of the genome; secondly the way in which genetic differences at the molecular level account for heritable variation in populations; and finally an explanation of how the genes control the metabolism and development of the whole organism. Professor Fincham takes as his theme the links between classical and molecular genetics, and throughout the book shows how the combination of these two approaches can be a powerful tool for the advancement of genetic research.

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Genetics: Analysis and Principles
Robert J. Brooker
Manufacturer: McGraw-Hill Science/Engineering/Math
ProductGroup: Book
Binding: Hardcover

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Book Description

Genetics: Analysis and Principles is a one-semester, introductory genetics textbook that takes an experimental approach to understanding genetics. By weaving one or two experiments into the narrative of each chapter, students can simultaneously explore the scientific method and understand the genetic principles that have been learned from these experiments.

Average customer rating:

Good Textbook
Nicely written, some VERY helpful diagrams

Genetics: Principles and Analysis
Daniel L. Hartl , and Elizabeth W. Jones
Manufacturer: Jones & Bartlett Pub
ProductGroup: Book
Binding: Hardcover

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Book Description

In recent decades, few disciplines have experienced the explosion of knowledge and research that genetics has. Inspired in part by controversies and the publicity that this new information generates, many of today's students come to a course in genetics with great enthusiasm. Sustaining this enthusiasm while at the same time teaching students about the beauty, logical clarity, and unity of the subject can be a challenge for any teacher. In the fourth edition of Genetics: Principles and Analysis, Dan Hartl and Beth Jones have written a text that will provide you and your students with a clear, comprehensive, rigorous, and balanced introduction to genetics at the college level. It is a guide to learning a critically important and sometimes difficult subject. But the tools for learning extend beyond the confines of the textbook. Your students will have the opportunity to become active participants in the learning process by making full use of today's teaching and learning technology. Developed as an integrated and unified program, no other textbook will engage your students and connect them to the subject of genetics like Hartl/Jones!

Customer Reviews:

Good Textbook.......2002-02-17

Unfortunately I sold this book during undergrad once my genetics course was over. Now at Medical School, I am rebuying it cause I know it works. Good explanations, pictures, ect. I would recommend it to anyone who wants a straight explanation...it's great if you are not a research based person.

Nicely written, some VERY helpful diagrams.......1999-06-21

Genetics is confusing. True or false? Genetics is quite enjoyable. True or false?

The answer can be true to either question, depending on which book you use to learn genetics for the first time.

Fortunately for me, our Biology department @BU chose Prof. Hartl's "Genetics." The book comes with nice diagrams to demonstrate certain concepts such as maternal effect and the Hardy Weinberg principle.

Of course, this book isn't perfect; it could use some improvements. Chapter 12--especially the section on bicoid genes in drosophila--took a while to slog through.

I suppose Prof. Hartl tried his best here, but this topic is confusing to begin with. It would have helped if pg 530-541 were rewritten. (I know that sounds very vague and fuzzy, but something about those pages just didn't click like other sections of the book).

Even if your Bio department doesn't use this version of "Genetics," I would recommend treating it as a reference book.

Good luck with genetics! Believe me, it CAN be fun and interesting....

-TheDeliman

Book Description

This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been written by developers or highly experienced end-users concerned with a diverse array of biological applications. The book should appeal to any researcher for whom costs and throughput in their genetics laboratory have become an issue.

Principles of Genome Analysis and Genomics

Average customer rating:

Clear and well-presented

Principles of Genome Analysis and Genomics
Sandy Primrose , and Richard M. Twyman
Manufacturer: Blackwell Publishing Limited
ProductGroup: Book
Binding: Paperback

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ASIN: 1405101202

Book Description

With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant.

Customer Reviews:

Clear and well-presented.......1999-08-06

Presents material in a succinct manner. A good read for an introduction to the subject.

Proteome Research: New Frontiers in Functional Genomics (Principles and Practice)

Average customer rating:

Good Concept Building book.

Proteome Research: New Frontiers in Functional Genomics (Principles and Practice)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

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ASIN: 3540627537

Book Description

Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.

Customer Reviews:

Good Concept Building book........2002-04-01

I bought this book to understand the computer science side of molecular biology. This book gives good treatment of the basics though if you are a programmer and want to get involved straight away, this book will be of little help.

This book helped me understand some concepts, and pointed me to some of the tools and databases that are currently in use in the bioinformatics business.

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