Developmental Biology, Eighth Edition (Developmental Biology)

Book Description

The Eighth Edition of Developmental Biology expands its coverage of the mechanisms of development, the roles that environmental factors play in development, the medical applications of our knowledge of development, and the roles that development plays in evolution, highlighting all the incredible advances that have been made in the last three years. Written primarily for undergraduate biology majors, it also serves to introduce graduate students and medical students to developmental biology.

A completely updated text integrates classical developmental biology with contemporary techniques, including new material on: stem cells niches; microRNAs; sperm-egg attraction and binding; induction and maintenance of pluripotency; pioneer transcription factors and the recruitment of nucleosome remodeling proteins; left-right gene expression asymmetry; heart chamber specification; neural crest cell specification and differentiation; somite formation; human brain growth genes; the syndetome; new sources of muscle precursor cells; newly discovered mechanisms of teratogenesis; the effects of endocrine disruptors on human development; sex determination pathways in the brain; the effects of maternal nutrition on gene expression and disease susceptibility in the adult offspring; controversies over digit specification in birds and dinosaurs and whether mammalian blastomere fate is biased at the first division; and much more. Included with every copy of the book is Vade Mecum2: An Interactive Guide to Developmental Biology. In addition to a wealth of interactive content, this updated version includes a new Teachers' and Student's Resource with PowerPoint® slides of chick whole mounts and serial sections. A searchable PDF file on the CD contains full citations for the book's literature cited, with links to PubMed. The CD also includes Mary Tyler's laboratory manual, Developmental Biology: A Guide for Experimental Study, Third Edition, in electronic (PDF) format. textbook and provides more information for advanced students, historical, philosophical, and ethical perspectives on issues in developmental biology, movies, interviews, Web links, and updates. The website includes the full bibliography of literature cited in the book (over 5,000 references), most of which are linked to their PubMed citations.

Customer Reviews:

It is impossible........2007-09-28

I had this mail to review a book that I would love to read. However I still did not receive it. And nobody is able to explain what happened to my book that bought the book in August. It will be my last purchaise at amazon.

Comprehensive, interesting and well illustrated.......2007-05-06

With a clear prose and a CD with links to all source material, this book is a great source for any biologist interested in the development of organisms, and how it was all figured out.

Needs streamlining.......2007-03-09

This book is a decent developmental textbook, but it focuses too little on explanation and too much on storytelling. While this style is appropriate in group talks, it wastes time when someone is trying to learn quickly and makes it difficult to find the useful pieces of information. The only way I have been able to use this book is with a highlighter at all times.

The text could also benefit from a reorganization. It seems that in order to get a good picture of the pathways that are recurring themes in development, one has to read the book out of order, and that can be confusing.

Other than that, it is factually accurate for the most part and has a sturdy binding, so it will last. The paper it's printed on isn't too great and ink/highlighter can show through, but not too badly.

Overall this is a good introduction to developmental biology, but it is not very useful as a quick reference or for someone trying to learn a specific organism quickly.

great.......2007-01-26

This book is easy to follow with great details about techniques and special topics in embryology. The CD is of great use for class and lab.

miss.......2006-07-24

This book offers a nice historical look at biology, but very little (if anything) about embryology is covered. The same can be said for the important development of anatomy. Sometimes it's best to read other reviews to find out if purchasing a book is the right decision or not. In this case, listen to the negative reviews. They're correct.

Average customer rating:

Atlas of Mouse Development
Matthew H. Kaufman
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Similar Items:

The Anatomical Basis of Mouse Development
Manipulating the Mouse Embryo: A Laboratory Manual
Mouse Development: Patterning, Morphogenesis, and Organogenesis
Molecular Cloning: A Laboratory Manual (3-Volume Set)
The Laboratory Mouse (Handbook of Experimental Animals)

ASIN: 0124020356

Book Description

Not since the early 1970s has there been an attempt to describe and illustrate the anatomy of the developing mouse embryo. More than ever such material is needed by biologists as they begin to unravel the molecular mechanisms underlying development and differentiation. After more than ten years of painstaking work, Matt Kaufman has completed The Atlas of Mouse Development--the definitive account of mouse embryology and development.
For all those researching or studying mammalian development, The Atlas of Mouse Development will be the standard reference work for many years to come.

Key Features
* Provides a comprehensive sequential account of the development of the mouse from pre-implantation to term
* Contains clear and concise descriptions of the anatomical features relevant to each stage of development
* Large format for easy use
* Contains explanatory notes and legends, and more than 180 meticulously labeled plates, 1,300 photographs of individual histological sections, and 200 electron micrographs, illustrating:
* Intermittent serial histological sections through embryos throughout embryogenesis and organogenesis
* Differentiation of specific organs and organ systems, including the spinal cord, eyes, gonads, kidneys, lungs and skeletal system
* External appearance of intact embryos throughout development

Manipulating the Mouse Embryo: A Laboratory Manual

Average customer rating:

The New Testament?

Manipulating the Mouse Embryo: A Laboratory Manual

Manufacturer: Cold Spring Harbor Laboratory Press
ProductGroup: Book
Binding: Paperback

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Similar Items:

Atlas of Mouse Development
Mouse Phenotypes: A Handbook of Mutation Analysis
The Laboratory Mouse (Handbook of Experimental Animals)
Molecular Cloning: A Laboratory Manual (3-Volume Set)
Mouse Development: Patterning, Morphogenesis, and Organogenesis

ASIN: 0879695919

Book Description

Regarded as the "Bible" of mammalian embryo manipulation techniques since the 1986 publication of the first edition of Manipulating the Mouse Embryo: A Laboratory Manual, the third edition of this essential laboratory resource has now been completely reorganized, rewritten, and updated by a new cast of authors. The result is a compilation of new, cutting-edge protocols that include embryonic stem cell production and genetic manipulation, mouse chimeras, mouse cloning, assisted reproduction strategies (including intracytoplasmic sperm injection and in vitro fertilization), whole embryo culture systems, electroporation, embryo and gamete cryopreservation and rederivation, and gene expression, as well as more extensive background information on the use of these techniques. The "gold standard" techniques for applying recombinant DNA technology to investigations of mammalian embryonic development included in the first two editions of this book are also updated and recast, as is the summary of the current state of understanding of mouse development at the molecular level. This book is the premier authoritative and comprehensive source of technical and theoretical guidance for mouse developmental biologists and geneticists and is an essential resource for newcomers to these fields.

Customer Reviews:

The New Testament?.......2004-01-20

A definitive summary of mouse development and simple, concise proven protocols. This is the best publication there is for this kind of work. It's much better than the 2nd, ed. I wish it had more of a troubleshooting focus, but I guess if you are in this line of work, you should be able to figure out problems yourself, or query the tg list.... I like how there are alternative strategies mentioned depending on how your lab is equiped (or not).

From Conception to Birth: A Life Unfolds

Average customer rating:

Wow! Impressive photos AND dialouge!
A Life Unfolds
Good
As incredible as being pregnant!
From Conception to Birth

From Conception to Birth: A Life Unfolds
Alexander Tsiaras
Manufacturer: Doubleday
ProductGroup: Book
Binding: Hardcover

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A Child Is Born
The InVision Guide to a Healthy Heart
The Architecture and Design of Man and Woman: The Marvel of the Human Body, Revealed
Watch Me Grow : A Unique, 3-Dimensional Week-by-Week Look at Your Baby's Behavior and Development in the Womb
In the Womb: Witness the Journey from Conception to Birth through Astonishing 3D Images

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Braun IRT 4020 ThermoScan Ear Thermometer

ASIN: 0385503180
Release Date: 2002-10-29

Book Description

The splendor and beauty of a child’s growth and development in the womb--seen through unforgettable images made possible by revolutionary advances in visualization technology

What’s happening with the baby now? All expectant parents ask this question throughout the exhilirating months of pregnancy. Fuzzy sonograms and doctor’s explanations can provide basic information, but through Alexander Tsiaras’ remarkable achievements in medical imaging technology, parents can see, for the first time, the awe-inspiring process of a new life unfolding, in stunning, vivid detail.

The milestones of pregnancy which before could only be described can now be witnessed: the heart’s first beats; the appearance of color in the eye; the emergence of toes and teeth; the brain and nervous system directing development; the first movement of tiny legs and arms; the first indications of gender; the wondrous symbiosis of mother and child; the symphony of the body’s systems coming into being and working in concert. The book tracks the development of a baby from the moment of conception, through the explosively complex early stages of development and the amazing stages of growth as the baby is nurtured by the mother, ending with the joy of birth.

All this is made possible by revolutions in two sciences. As biologists have decoded the molecular basis of life, computer scientists have developed non-invasive, three-dimensional techniques for visualizing the body. Alexander Tsiaras has been a pioneer in merging these explorations and discoveries. He has created a virtual camera studio that enables him to view a human body or any part of it individually, scan it, enlarge it, rotate it, adjust its transparency so that we can view inside a living being, and light it from any angle. The result is an ability to illuminate the unseen elements that make us who we are, and the miraculous images in From Conception to Birth.

Customer Reviews:

Wow! Impressive photos AND dialouge!.......2007-06-18

I hesitated to buy this book because I heard some of the negative reviews, such as "the Nielson book is better" and "the images are fake, clay". However, I found it is more MUCH more informative and interesting than "A Child Is Born". It is modern, cleverly written, and really worthwhile as a coffe table book or baby shower gift. The format of the book is mostly photograph/art, with small paragraphs of information. My husband has been reading this book about what is happening to the baby every morning at breakfast, because it is written day by day, which is different than most pregnacy guides. It is free from advice, it is only factual.

A Life Unfolds.......2007-05-25

I was very happy with the book. The photographs were amazing!

Good.......2007-01-20

The photography is definitely the highlight of this book. It also gives you a great biology review. Perhaps more than the average person would want to know. My only criticism is that it focused more on the embryonic development than on fetal development. I realize that most of the fascinating transformations occur in the first trimester but I still was hoping to see great photos of the second and third. I preferred Beginning Life by Geraldine Flanagan to this book.

As incredible as being pregnant!.......2007-01-10

This book has got all the info you need when you are expecting. The pictures are so cool, my son loved to look at them to see what his sibling looked like at each stage. Very informative and eye opening!

From Conception to Birth.......2007-01-03

Amazing pictures! Great for future parents, parents or for anyone else who have interest in learning a bit more.

The Primal Teen: What the New Discoveries about the Teenage Brain Tell Us about Our Kids

Average customer rating:

Yet Another Ridiculous Parenting Book
A must-read for every parent!
Not an Instruction Manual
Good Read for Parents, Not Neurologists
So That's What's Going On in Their Heads!

The Primal Teen: What the New Discoveries about the Teenage Brain Tell Us about Our Kids
Barbara Strauch
Manufacturer: Anchor
ProductGroup: Book
Binding: Paperback

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WHY Do They Act That Way?: A Survival Guide to the Adolescent Brain for You and Your Teen
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Yes, Your Teen is Crazy!: Loving Your Kid Without Losing Your Mind
A Mind at a Time

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philosophy hope in a jar daily moisturizer

ASIN: 0385721609
Release Date: 2004-09-14

Book Description

For anyone who has ever puzzled over the mysterious and often infuriating behavior of a teenager comes a groundbreaking look at the teenage brain written by the medical science and health editor for The New York Times. While many members of the scientific community have long held that the growing pains of adolescence are primarily psychological, Barbara Strauch highlights the physical nature of the transformation, offering parents and educators a new perspective on erratic teenage behavior. Using plain language, Strauch draws upon the latest scientific discoveries to make the case that the changes the brain goes through during adolescence are as dramatic and crucial as those that take place in the first two years of life, and that teenagers are not entirely responsible for their sullen, rebellious, and moody ways. Featuring interviews with scientists, teenagers, parents, and teachers, The Primal Teen explores common challenges–why teens go from articulate and mature one day to morose and unreachable the next, why they engage in risky behavior–and offers practical strategies to help manage these formative and often difficult years.

Customer Reviews:

Yet Another Ridiculous Parenting Book.......2006-12-01

The is yet another book premised on the assumption that your teen (or child) is some kind of alien. Remember -- you were once a child and a teen yourself, and your child will eventually be an adult, and maybe even a parent. Just relate to your child as a person, and forget about this book.

A must-read for every parent!.......2006-05-04

As parents of teens, we tend to think that--by now--we have pretty much figured out what makes our kids tick...hormones, immaturity, psicological issues...right? Well, maybe that is only part of the picture. This books does a wonderful job of going beyond that, to the neurological foundation of behavior itself. It clearly explains the ramifications of the changes that are going on at a neurological level in the brain of teens and how that, consequently, translates into "teen behavior".
Your kid is not "crazy"...their frontal cortex just needs more time to develop! A reassuring read for every parent!

Not an Instruction Manual.......2006-03-16

Strauch's book answers many questions as regards my teens' behaviors. My last one at home is 16; I purchsed this book to help me understand what is happening within that skull of his. Strauch utilizes her research to not only explain what my own child is going through but also helps to clarify the behavior of youth today as far as impulsivity, criminality, and various other compelling and noteworthy up-to-the-minute pertinent and important information we need to help our teenagers be successful in this day and age. The book is written somewhat like an investigative report, with a humourous punch, and is easily read by parents and teachers alike. It is an enjoyable and worthy read.

Good Read for Parents, Not Neurologists.......2006-02-23

This was a good read for parents of teens or pre-adolescents who are not in the medical field or some related field. The author is not a researcher but a journalist putting together what they've learned about the topic. (Some parents may have already done this for themselves.) It's not as detailed as someone well-read on the topic may hope, but for someone just becoming interested, perhaps someone experiencing shocking episodes in their own home with their own primal teen, it's a good starter book! Glad she put it together. Hopefully there's more to come with more neurological detail.

So That's What's Going On in Their Heads!.......2005-05-13

This book has helped me understand so much about what is going on with my teen! I could not put this book down. Now when my son does something odd, I just think, well at least I know why. Of course their is still your active parenting involved, but you know how to approach things better, and with an understanding of what may, or may not, have been going on in their little teenage brains. Buy it.

Color Atlas of Anatomy: A Photographic Study of the Human Body

Average customer rating:

A must for anatomy
love this book
GREAT BOOK, EVEN GREATER IF YOU OWN ONE!!!!!!!!!
Two sided ...
A great anatomy text

Color Atlas of Anatomy: A Photographic Study of the Human Body
Johannes W Rohen , Chihiro Yokochi , Elke Lütjen-Drecoll , and Lynn J Romrell
Manufacturer: Lippincott Williams & Wilkins
ProductGroup: Book
Binding: Hardcover

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Similar Items:

Clinically Oriented Anatomy (5th Edition)
Atlas of Human Anatomy: With Netteranatomy.com (Netter Basic Science)
BRS Gross Anatomy (Board Review Series)
Gray's Anatomy for Students
Grant's Dissector

ASIN: 0781731941

Book Description

The on-going core of this atlas is its standard of realistic illustrations that portray anatomical relationships. Photographs of actual cadaver dissections along with numerous schematic drawings aid the student in anatomic orientation. Chapters are organized by region, in order of a typical dissection. Each chapter contains two sections: a description and illustration of organs, and a depiction of those organs within the regional anatomy. New to this edition is an increase of MRI pictures, approximately 30 schematic drawings made even more precise, and an updated text where appropriate. A Brandon-Hill recommended title.

Customer Reviews:

A must for anatomy.......2007-10-03

I consider this book to be a must for any anatomy student. The pictures are exactly what you will see when you enter the lab.

love this book.......2007-03-28

In case it isn't clear from the description or title, this is an anatomy atlas made up of photos of actual human bodies. I don't know why we didn't have this in A&P. Fascinating, and a nicely produced book as well.

GREAT BOOK, EVEN GREATER IF YOU OWN ONE!!!!!!!!!.......2006-03-26

AM A SECOND YEAR STUDENT OF ANATOMY, AND AM GOING INTO THE RADIOGRAPHER TECH PROGRAM AT MY SHCOOL I JUST BOUGHT THIS BOOK AFTER SEEING IT, AFTER SOMEONE BOUGHT IT. SO I ORDERED MY OWN COPY, AND AM TOTALLY BLOWN AWAY BY THE PERCISION OF THE BOOKS DETAIL ON EVERY SINGLE PHOTOGRAPH. I THINK THIS WILL BE A DEFINATE KEEPER, AND IF YOU ARE LOOKING AT THE PRICE WITH A SIGH, DON'T JUST GET IT AND ENJOY!~

Also recommended: ALSO STRONGLY RECOMMEND THE COLOR ATLAS OF HUMAN ANATOMY by Wolf-Heidegger!!!!!!!!

Two sided ..........2006-03-25

My opinion about this book is a bit two sided and that's why:
I bought this one for my first year medical anatomy course and was a little mystified by it, at least at the beginning. I couldn't really understand what is going on in the corpse and as I looked into this book the sight was "cleaner" but similar. Naturally I put it away for a while and used Netter which was excellent.
A while after I became familiar with gross anatomical structures I opened it again, and only then I undestood what is going on inside, and only then I understood how great this book is!
Especially nice and logical where the drawings and explanations included.
Thus, my conclusion is that this book can be a great find for a student who has already taken the course, for a review or other purpose, but for a true beginner in this field it is almost the same as looking at the body.
In my opinion, to make an Atlas understandable for the beginner, it must NOT be real but must present the human body as seen through the eyes of the student. This job is perfectly done by Netter.

A great anatomy text.......2005-09-29

I agree completely with the review by Gerald J. Nora. The book is first rate and does a fantastic job of showing the "real" anatomy as opposed to drawings where the artist takes some liberties. The text begins simple and builds upon it. The only down side is that the labels are not ordered in a top down fashion. For example, the labels may be: 3, 2, 4, 8, 7, 6, 5 which can be confusing. Overall the book is highly recommended as a reference to a traditional anatomy text.

Average customer rating:

Essentials of Stem Cell Biology
Review by New England Journal of Medicine
Essentials of Stem Cell Biology, First Edition

Essentials of Stem Cell Biology

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0120884429
Release Date: 2005-08-26

Book Description

This abridged version of the bestselling reference Handbook of Stem Cells, Two-Volume Set attempts to incorporate all the essential subject matter of the original two-volume edition in a single volume. The material has been reworked in an accessible format suitable for students and general readers interested in following the latest advances in stem cells, including full color presentation throughout. Although some extra language and chapters have been deleted, rigorous effort has been made to retain from the original two-volume set the material pertinent to the understanding of this exciting area of biology.

The organization of the book remains largely unchanged, combining the prerequisites for a general understanding of adult and embryonic stem cells; the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations; as well as a presentation by the world's experts of what is currently known about each specific organ system.

* Full-color presentation througout
* Each chapter begins with 3-5 defined glossary terms, and all of the terms are collected in a comprehensive list within the book
* References have been eliminated - now there are about 10 bibliographic entries per chapter

Customer Reviews:

Essentials of Stem Cell Biology.......2007-01-03

Well balanced, superbly written muiltiauthored textbook. Excellent discussion of basic cell biology of embryonic and adult (nonembryonic) stem cells from multiple sources, laboratory techniques and potential clinical applications and includes a chapter on ethics and national policy for stem cell research. Suitable for students, clinicians as well as experienced stem cell biologists.

Review by New England Journal of Medicine.......2006-08-01

"Essentials of Stem Cell Biology belongs on the shelf of every researcher, clinician, and student who is interested in new developments in stem cell research and the related treatment options that are being developed."

Essentials of Stem Cell Biology, First Edition.......2006-03-20

The best for Stem Cell Biology for student or for someone who like to learn new things.

The Regulatory Genome: Gene Regulatory Networks In Development And Evolution

Average customer rating:

A real theory of biology and evolution

The Regulatory Genome: Gene Regulatory Networks In Development And Evolution
Eric H. Davidson
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0120885638

Book Description

Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology.

The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market.

* The only book in the market that is solely devoted to the genomic regulatory code for animal development
* Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding
* Presents a comprehensive treatment of molecular control elements that determine the function of genes
* Provides a comparative treatment of development, based on principles rather than description of developmental processes
* Considers the evolutionary processes in terms of the structural properties of gene regulatory networks
* Includes 42 full-color descriptive figures and diagrams

Customer Reviews:

A real theory of biology and evolution.......2007-03-23

This book will be a revelation to any biologist who has not been reading the literature on development and embryology attentively. Davidson eloquently articulates a real theory of the mechanism by which the genome computes the embryologic development of bilaterian animals. The argument is carefully developed from simple principles to more complex implications. The figures are a major part of the book's exposition, and repay very careful reading of the legends along with the associated text. The references are as current as 2006, so the book is quite cutting edge in its outlook. I heartily recommend it to any biologically sophisticated reader. It does presume elementary knowledge about biochemistry and molecular biology at about the freshman/sophomore college level. Enjoy!

Average customer rating:

Excellent!
So, what's your story?
We forget that we're animals....
Another Look at Knowledge.
A Real "Gem" (Apologies to D. C. Stove)

Tree of Knowledge
Humberto R. Maturana , and Francisco Varela
Manufacturer: Shambhala
ProductGroup: Book
Binding: Paperback

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High Output Management
Steps to an Ecology of Mind: Collected Essays in Anthropology, Psychiatry, Evolution, and Epistemology

ASIN: 0877736421
Release Date: 1992-03-31

Book Description

"Knowing how we know" is the subject of this book. Its authors present a new view of cognition that has important social and ethical implications, for, they assert, the only world we humans can have is the one we create together through the actions of our coexistence. Written for a general audience as well as for students, scholars, and scientists and abundantly illustrated with examples from biology, linguistics, and new social and cultural phenomena, this revised edition includes a new afterword by Dr. Varela, in which he discusses the effect the book has had in the years since its first publication.

Customer Reviews:

Excellent!.......2007-09-25

This book, if read carefully, will change the way that you look at the world. It is powerful and insightful.

So, what's your story?.......2007-05-03

I came to this book years ago through, of all things, a two-year course in business and sales, for which it was required reading along with "Computers and Cognition", another eye-opener; the latter anticipated the current transactional nature of the Internet. You might ask how a work as theoretical and speculative as "Tree of Knowledge" could be part of a pragmatic and hardnosed business course, and that is one key to its attraction for me: as intellectually intriguing as the ideas and assertions in this book are, even more engaging is how they might actually change the way we act in the world.

The authors drill down to molecular biology and then carefully build upward their premise that we construct the worlds we live in out of language. Each of us exists inside a story we tell ourselves about the way the world is, and we are completely contained within that story. In that sense, we interact with other people through the way our stories talk to their stories. And the success of our relationships and the effectiveness with which we act in our world is dependent on how well we can recognize the stories of others and understand the nature of our own story.

This is good news, once we recognize it, because we are a narrative species. On my way to work in the morning, I am telling myself a story about the way I want my day to go: what I expect, what I want to accomplish, how I will confront the challenges along the way. The story I tell myself about my life has heroes and villains, goals and challenges, grand themes and petty foibles. The more we understand the grand, rich, complex stories those around us are telling themselves, the more we can overcome misunderstandings, conflicts and cultural dissonance - the more, in a sense, we can constuct a meta-story that serves us all as human beings.

This is not a quick and simple read, but it is so logically and carefully laid out that I never felt lost along the journey. It is a wonderful book to read in tandem with a friend, or as part of a book club. The discussion and the "aha!" experiences it prompts make for a lively exploration of its ideas. Part of the joy of "Tree of Knowledge" is its potential for promoting tolerance of those different from us, through recognition of what drives their story rather than through compromising our own values.

"ladylucero", in her review, noted that "Tree of Knowledge" is required reading in some American universities. I read that in the authors' native Chile it is even taught in high schools. This, I believe, is good news: the earlier in life we recognize how our individual stories drive our hopes and expectations, our fears and disappointments, the more capable we will be of living well with our fellow human beings.

We forget that we're animals...........2005-09-20

Amazing piece of work. Very slow reading... meaty. Well written. This should be the primer for every field of study in every country. We are first and foremost biological organisms. We live in language like fish in a fish bowl. Fish can't distinguish water. It defines them. Same with language with human beings... we are defined by our listening and speaking and don't have a clue.

The illustrations are the best... I think it is one of the most important books of our time.

Another Look at Knowledge........2004-12-14

Excellent and superb are words that come to mind while reviewing this work. The authors, Drs. Humberto R. Maturana (biologist, University of Chile) and Francisco J. Varela (Foundation de France Professor of Cognitive Sciences and Epistemology, Paris) attempted and succeeded in providing a clear and concise work in a difficult field. Their goal was to "propose a way of seeing cognition not as a representation of the world 'out there,' but rather as an ongoing bringing forth of a world through the process of living itself."

Knowing how we know, or how we perceive is the subject of this intriguing work. In writing on this subject, the authors present a refreshing and new approach to cognition-one which has dramatic cultural, social and ethical ramifications.

The work, originally published in 1987 and re-released in 1992 as a revised edition, is attractive, colorful and well-illustrated. Unlike many books, whose pictures, graphs and figures merely fill space, each illustration performs a beneficial and needed service. In ten chapters, the reader is led slowly through the concepts and disciplines of perception, classification, heredity, biology, psychology, sociology and philosophy.

Since its initial publication, The Tree of Knowledge has received favorable attention from the public, has been out of stock in most bookstores and has been used as an undergraduate text at the University of California. While stimulating the imagination of readers it has, however, not received the scholarly acclaim it richly deserves.

Dr. Carl Edwin Lindgren, DEd
Former Member of the Royal Institution of Great Britain

A Real "Gem" (Apologies to D. C. Stove).......2004-11-18

Maturana's antinomous conclusions are based on the following (embarassingly) invalid inference:

1. All knowing is doing and all doing is knowing
2. Therefore, we can't know the way the world is.

They might just as well have argued:

1. I must use my eyes to see the world.
2. Therefore, I can't see the world.

The Mouse in Biomedical Research, Volume 1-4, Second Edition (American College of Laboratory Animal Medicine) (American College of Laboratory Animal Medicine)

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The Mouse in Biomedical Research, Volume 1-4, Second Edition (American College of Laboratory Animal Medicine) (American College of Laboratory Animal Medicine)

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 012369454X

Book Description

In no other species of animal has such a wealth of experimental data been utilized for scientific pursuits. Now in its Second Edition, this Four Volume Set is dedicated to the understanding of the mouse and its role in scientific research. This valuable compendium serves as a standard reference source of information for students embarking on scientific careers, specialists in laboratory animal science, technicians in both animal care and research, and the broad scientific community.

This set is also sold individually and covers History, Wild Mice, and Genetics; Diseases; Normative Biology, Husbandry, and Models; and Immunology.

Volume 1: History, Wild Mice, and Genetics
KEY FEATURES:
A primer for scientists new to the field of mouse research
Information about the history, biology and genomics of the laboratory mouse (Mus musculus)
Mouse origins and relationships covered in chapters on history, evolutionary taxonomy and wild mice
Mouse genetics and genomics discussed in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome
Use of the mouse as a model system for basic biomedical research described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation

Volume 2: Diseases
KEY FEATURES:
New format by discussing specific disease causing microorganisms versus the format used in the first edition which discussed infectious diseases affecting specific organs and tissues
Consists of 26 chapters subdivided into RNA viruses and DNA viruses, mycotic, and parasitic infections.
Provides updates on pathogenesis, epidemiology and prevention of previously recognized murine pathogens
Offers information on newly recognized disease-causing organisms: mouse parvovirus, cilia associated respiratory bacilli and Helicobacter

Volume 3: Normative Biology, Husbandry, and Models
KEY FEATURES:
Encompasses 23 chapters with a broad overview on the laboratory mouses normative biology, husbandry, and its use as a model in biomedical research.
Includes chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry.
Discusses management, nutrition, gnotobiotics and disease surveillance
Provides analysis of the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases

Volume 4: Immunology
KEY FEATURES:
A complete new addition to this series, dedicated to mouse immunology including both the innate and adaptive immune systems
Based on the mouse as a choice model when studying immunity in man-arguably more is known about the immune system in mice than any other species except man
Chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells

NEW TO THIS EDITION:
* Over 50% new material
* Each volume contains 4-color page inserts with indispensable figures
* Greatly expanded sections on genetics including: the mouse genome, gene mapping, and gene therapy
* Information on newly recognized disease-causing organisms, such as mouse parvovirus and Helicobacter
* A volume entirely devoted to mouse immunology
* New section on stem cell biology
* Each of the four volumes are available individually

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